Article
Quantitative trait loci with age-specific effects on fecundity in Drosophila melanogaster.
Genetics - 1 Mar 2006
Leips Jeff, Gilligan Paul, Mackay Trudy F C
Abstract excerpt
Life-history theory and evolutionary theories of aging assume the existence of alleles with age-specific effects on fitness. While various studies have documented age-related changes in the genetic contribution to variation in fitness components, we know very little about the underlying genetic architecture of such changes. We used a set of recombinant inbred lines to map and characterize the effects of...
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