Article
Norepinephrine transporter: a candidate gene for initial ethanol sensitivity in inbred long-sleep and short-sleep mice.
Alcoholism, clinical and experimental research - 1 Oct 2005
Haughey Heather M, Kaiser Alan L, Johnson Thomas E, Bennett Beth, Sikela James M, Zahniser Nancy R
Abstract excerpt
BACKGROUND: Altered noradrenergic neurotransmission is associated with depression and may contribute to drug abuse and alcoholism. Differential initial sensitivity to ethanol is an important predictor of risk for future alcoholism, making the inbred long-sleep (ILS) and inbred short-sleep (ISS) mice a useful model for identifying genes that may contribute to alcoholism. METHODS: In this study, molecular...
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