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Article

Cdc37 interacts with the glycine-rich loop of Hsp90 client kinases.

Molecular and cellular biology - 1 May 2006

Terasawa Kazuya, Yoshimatsu Katsuhiko, Iemura Shun-Ichiro, Natsume Tohru, Tanaka Keiji, Minami Yasufumi

Abstract excerpt

Recently, we identified a client-binding site of Cdc37 that is required for its association with protein kinases. Phage display technology and liquid chromatography-tandem mass spectrometry (which identifies a total of 33 proteins) consistently identify a unique sequence, GXFG, as a Cdc37-interacting motif that occurs in the canonical glycine-rich loop (GXGXXG) of protein kinases, regardless of their dependence...

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Source

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Identifiers

PMID: 16611982
DOI: 10.1128/MCB.26.9.3378-3389.2006
PMCID: PMC1447410

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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