Article
[Polymorphism Gly460Trp of alpha-adducin gene and predisposition to essential hypertension. The role of gene-environment interactions in the development of the disease in Russian population].
Kardiologiia - 1 Jan 2011
Polonikov A V, Ushachev D V, Shestakov A M, Ivanov V P, Solodilova M A, Vialykh E K, Kozhukhov M A, Kolesnikova O E, Ivakin V E, Katargina L N, Kabanina V A, Kupriianova Ia S, Tevs D S
Abstract excerpt
In this study we for the first time in Russian population elucidated association between G460W polymorphism of -adducin gene (ADD1) and risk of development of hypertensive disease (HD). DNA samples from 205 patients with HD and 207 healthy nonrelated individuals of Russian nationality were genotyped for G460W polymorphism of ADD1 gene by polymerase chain reaction and restriction analysis. We detected no...
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