Article
Review article: thiopurines in inflammatory bowel disease.
Alimentary pharmacology & therapeutics - 1 Sept 2006
Derijks L J J, Gilissen L P L, Hooymans P M, Hommes D W
Abstract excerpt
BACKGROUND: In the past 10-20 years, knowledge of both thiopurine pharmacology and -pharmacogenetics has been extended dramatically and used to develop new strategies to improve efficacy and reduce toxicity. AIM: To review thiopurine efficacy, toxicity, pharmacology, pharmacogenetics, interactions in patients with inflammatory bowel disease. Special attention was paid to new strategies for optimization of...
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