Article
Nuclear presence of adhesion-/growth-regulatory galectins in normal/malignant cells of squamous epithelial origin.
Histochemistry and cell biology - 1 Jan 2006
Smetana Karel, Dvoránková Barbora, Chovanec Martin, Boucek Jan, Klíma Jirí, Motlík Jan, Lensch Martin, Kaltner Herbert, André Sabine, Gabius Hans Joachim
Abstract excerpt
Cellular activities in the regulation of growth or adhesion/migration involve protein (lectin)-carbohydrate recognition at the cell surface. Members of the galectin family of endogenous lectins additionally bind distinct intracellular ligands. These interactions with protein targets explain the relevance of their nuclear and cytoplasmic presence. Expression profiling for galectins and accessible binding sites is...
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