Article
Defining the glycophenotype of squamous epithelia using plant and mammalian lectins. Differentiation-dependent expression of alpha2,6- and alpha2,3-linked N-acetylneuraminic acid in squamous epithelia and carcinomas, and its differential effect on binding of the endogenous lectins galectins-1 and -3.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Dec 2002
Holíková Zuzana, Hrdlicková-Cela Enkela, Plzák Jan, Smetana Karel, Betka Jan, Dvoránková Barbora, Esner Milan, Wasano Kojiro, André Sabine, Kaltner Herbert, Motlík Jan, Hercogová Jana, Kodet Roman, Gabius Hans-Joachim
Abstract excerpt
A thorough characterization of the properties of squamous epithelial cells is necessary in order to improve our understanding of the functional aspects of normal development and malignant aberrations. Up to now, studies have focused almost exclusively on monitoring distinct protein markers. With our growing awareness of the coding function of glycan chains of cellular glycoconjugates and their interaction with...
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