Article
Expression of vascular endothelial growth factor (VEGF) and its receptors in thyroid carcinomas of follicular origin: a potential autocrine loop.
European journal of endocrinology - 1 Nov 2005
Vieira Joaquim Miguel, Santos Susana C Rosa, Espadinha Carla, Correia Isabel, Vag Tibor, Casalou Cristina, Cavaco Branca Maria, Catarino Ana Luiísa, Dias Sérgio, Leite Valeriano
Abstract excerpt
OBJECTIVE: The aim of this study was to clarify the role of vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) pathways in thyroid tumourigenesis. METHODS: We examined VEGF, VEGFR-1 and VEGFR-2 expression on 34 papillary thyroid carcinomas (PTCs), 18 follicular thyroid carcinomas (FTCs), eight poorly differentiated thyroid carcinomas (PDTCs) and on a thyroid tumour-derived cell line (NPA'87) by...
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