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Article

Fas/Fas ligand gene polymorphism in patients with papillary thyroid cancer in the Turkish population.

Journal of endocrinological investigation - 1 May 2007

Erdogan M, Karadeniz M, Berdeli A, Tamsel S, Ertan Y, Uluer H, Yilmaz C, Tuzun M, Kabalak T, Ozgen A G

Abstract excerpt

OBJECTIVE: Fas ligand (FasL) is an apoptotic agent and a member of tumor necrosis factor (TNF) family. FasL exists in cytotoxic T lymphocyte (CTL) and natural killer (NK) cells, and it is increased in tumor cell membrane. On the contrary, CTL and NK are bound to Fas on the surfaces of cell membrane; this triggers apoptosis in cytotoxic cells and leads to their death. This system plays an important role in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Restriction Fragment Length

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Source

Identifiers

PMID: 17598974
DOI: 10.1007/BF03346319

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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