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A VEGFR2 Antagonist Inhibits Cell Proliferation, Migration, and Invasion by Blocking the PI3K-Akt and MAPK Signaling Pathways in Thyroid Cancer

2021-06-22

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Vascular endothelial growth factor receptor-2 (VEGFR2)-mediated signaling cascades are involved in proliferation, migration, survival, and permeability changes in vascular endothelial cells. It was thought that VEGFR2 antagonists exerted their antitumor effects by inhibiting angiogenesis in tumor tissues. However, some recent studies have found that they have si...

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Literature Corpus work
90f13016-573b-5b38-bebc-ff6eda4f0a90
DOI
10.21203/rs.3.rs-625662/v1
Open publication

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A VEGFR2 Antagonist Inhibits Cell Proliferation, Migration, and Invasion by Blocking the PI3K-Akt and MAPK Signaling Pathways in Thyroid CancerDOI 10.21203/rs.3.rs-625662/v1
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