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Article

Differential signaling mechanisms regulate expression of CC chemokine receptor-2 during monocyte maturation.

1 Jan 2005

Abstract excerpt

BACKGROUND: Peripheral blood monocytes and monocyte-derived macrophages are key regulatory components in many chronic inflammatory pathologies of the vasculature including the formation of atherosclerotic lesions. However, the molecular and biochemical events underlying monocyte maturation are not fully understood. METHODS: We have used freshly isolated human monocytes and the model human monocyte cell line,...

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PMID: 16259633
DOI: 10.1186/1476-9255-2-14

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