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Hedgehog signaling pathway as a potential target in the treatment of advanced gastric cancer

1 Jun 2017

Abstract excerpt

The sonic hedgehog signaling pathway is critical for cell proliferation, cell differentiation, and organ development during embryogenesis. Aberrant activation of the sonic hedgehog pathway has been associated with a variety of human cancers. Currently, there is no target molecular drug that clinically affects sonic hedgehog activation in patients with gastric cancer. In this review, we will focus on the current...

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PMID: 28621241
DOI: 10.1177/1010428317692266

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