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Article

Vehicular exhaust particles promote allergic airway inflammation through an aryl hydrocarbon receptor-notch signaling cascade.

The Journal of allergy and clinical immunology - 1 Aug 2015

Xia Mingcan, Viera-Hutchins Loida, Garcia-Lloret Maria, Noval Rivas Magali, Wise Petra, McGhee Sean A, Chatila Zena K, Daher Nancy, Sioutas Constantinos, Chatila Talal A

Abstract excerpt

BACKGROUND: Traffic-related particulate matter (PM) has been linked to a heightened incidence of asthma and allergic diseases. However, the molecular mechanisms by which PM exposure promotes allergic diseases remain elusive. OBJECTIVE: We sought to determine the expression, function, and regulation of pathways involved in promotion of allergic airway inflammation by PM. METHODS: We used gene expression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25825216
DOI: 10.1016/j.jaci.2015.02.014
PMCID: PMC4530027

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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