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Article

HLA-C and killer cell immunoglobulin-like receptor genes in idiopathic bronchiectasis.

American journal of respiratory and critical care medicine - 1 Feb 2006

Boyton Rosemary J, Smith John, Ward Rosemary, Jones Meinir, Ozerovitch Lorraine, Wilson Robert, Rose Marlene, Trowsdale John, Altmann Daniel M

Abstract excerpt

RATIONALE: In idiopathic bronchiectasis, lung inflammation and chronic bacterial infection lead to progressive lung damage. A possible role for natural killer (NK) cells is suggested by the observation that familial bronchiectasis occurs in a rare group of individuals with impaired HLA class I expression and consequent NK cell dysfunction. OBJECTIVE: Because the HLA-C locus and killer cell immunoglobulin-like...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16254274
DOI: 10.1164/rccm.200501-124OC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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