Article
The killer immunoglobulin-like receptor (KIR) group A haplotype is associated with bronchiolitis obliterans syndrome after lung transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 Sept 2008
Kwakkel-van Erp Johanna M, van de Graaf Ed A, Paantjens Annelieke W M, van Ginkel Walter G J, Schellekens Jennifer, van Kessel Diana A, van den Bosch Jules M M, Otten Henny G
Abstract excerpt
BACKGROUND: The development of bronchiolitis obliterans syndrome (BOS) after lung transplantation is associated with viral infections. Natural killer (NK) cells are involved in the lysis of viral infected cells, and their activation is largely controlled by activating and inhibitory killer immunoglobulin-like receptors (KIRs). We hypothesized that KIR ligand incompatibility and recipients' individual KIRs could...
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