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Article

Prognostic value of activated Akt expression in oral squamous cell carcinoma

27 Oct 2005

Abstract excerpt

BACKGROUND: Akt is a serine/threonine kinase that plays an important role in tumorigenesis and influences prognosis in several cancers. However, its importance in oral squamous cell carcinomas (OSCC) has not been elucidated. AIM: To investigate the association between the expression of activated Akt, clinicopathological factors, and E-cadherin, PCNA (proliferating cell nuclear antigen), and VEGF (vascular...

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PMID: 16254112
DOI: 10.1136/jcp.2004.024786

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