Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Retrograde response to mitochondrial dysfunction is separable from TOR1/2 regulation of retrograde gene expression.

The Journal of biological chemistry - 30 Dec 2005

Giannattasio Sergio, Liu Zhengchang, Thornton Janet, Butow Ronald A

Abstract excerpt

Retrograde (RTG) signaling senses mitochondrial dysfunction and initiates readjustments of carbohydrate and nitrogen metabolism through nuclear accumulation of the heterodimeric transcription factors, Rtg1/3p. The RTG pathway is also linked to target of rapamycin (TOR) signaling, among whose activities is transcriptional control of nitrogen catabolite repression (NCR)-sensitive genes. To investigate the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Share to Dimerization

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Glutamate-Ammonia Ligase

Share to Glutamates

Share to Glutamine

Share to Histidine

Share to Nitrogen

Share to Phosphotransferases (Alcohol Group Acceptor)

Source

Identifiers

PMID: 16253991
DOI: 10.1074/jbc.M509187200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Retrograde response to mitochondrial dysfunction is separable from TOR1/2 regulation of retrograde gene expression.PMID 16253991Read ↗

Retrograde regulation of multidrug resistance in Saccharomyces cerevisiae.Semantic proximity Read ↗

Mechanism of metabolic control. Target of rapamycin signaling links nitrogen quality to the activity of the Rtg1 and Rtg3 transcription factors.Semantic proximity Read ↗

Vesicular Trafficking Systems Impact TORC1-Controlled Transcriptional Programs in Saccharomyces cerevisiae.Semantic proximity Read ↗

RTG1 and RTG2: two yeast genes required for a novel path of communication from mitochondria to the nucleus.Semantic proximity Read ↗

A transcriptional switch in the expression of yeast tricarboxylic acid cycle genes in response to a reduction or loss of respiratory function.Semantic proximity Read ↗

RTG genes in yeast that function in communication between mitochondria and the nucleus are also required for expression of genes encoding peroxisomal proteins.Semantic proximity Read ↗

The retrograde response links metabolism with stress responses, chromatin-dependent gene activation, and genome stability in yeast aging.Semantic proximity Read ↗

Tor signaling and nutrient-based signals converge on Mks1p phosphorylation to regulate expression of Rtg1.Rtg3p-dependent target genes.Semantic proximity Read ↗

The TOR signaling cascade regulates gene expression in response to nutrients.Semantic proximity Read ↗

Target of Rapamycin (TOR) Regulates Growth in Response to Nutritional SignalsSemantic proximity Read ↗

Accounting for strain-specific differences during RTG target gene regulation in Saccharomyces cerevisiae.Semantic proximity Read ↗

Ammonia regulates VID30 expression and Vid30p function shifts nitrogen metabolism toward glutamate formation especially when Saccharomyces cerevisiae is grown in low concentrations of ammonia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.