Article
RTG genes in yeast that function in communication between mitochondria and the nucleus are also required for expression of genes encoding peroxisomal proteins.
The Journal of biological chemistry - 28 Jul 1995
Chelstowska A, Butow R A
Abstract excerpt
In Saccharomyces cerevisiae cells with dysfunctional mitochondria, such as in petites, the CIT2 gene encoding the peroxisomal glyoxylate cycle enzyme, citrate synthase 2 (CS2), is transcriptionally activated by as much as 30-fold, a phenomenon we call retrograde regulation. Two genes, RTG1 and RT...
Topics
- Alleles
- Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
- Cell Nucleus
- Citrate (si)-Synthase
- Citric Acid Cycle
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Intracellular Signaling Peptides and Proteins
- Malate Dehydrogenase
- Membrane Proteins
- Microbodies
- Mitochondria
- Oleic Acid
- Oleic Acids
- RNA, Messenger
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Transcription Factors