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Article

Transmembrane domain-induced oligomerization is crucial for the functions of syndecan-2 and syndecan-4.

The Journal of biological chemistry - 30 Dec 2005

Choi Sungmun, Lee Eunjung, Kwon Soojin, Park Haein, Yi Jae Youn, Kim Seungin, Han Inn-Oc, Yun Yungdae, Oh Eok-Soo

Abstract excerpt

The syndecans are known to form homologous oligomers that may be important for their functions. We have therefore determined the role of oligomerization of syndecan-2 and syndecan-4. A series of glutathione S-transferase-syndecan-2 and syndecan-4 chimeric proteins showed that all syndecan constructs containing the transmembrane domain formed SDS-resistant dimers, but not those lacking it. SDS-resistant dimer...

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PMID: 16253987
DOI: 10.1074/jbc.M509238200

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SDS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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