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Article

FGF upregulates osteopontin in epiphyseal growth plate chondrocytes: implications for endochondral ossification.

Matrix biology : journal of the International Society for Matrix Biology - 1 Dec 2005

Weizmann S, Tong A, Reich A, Genina O, Yayon A, Monsonego-Ornan E

Abstract excerpt

Fibroblast growth factor receptor 3 (FGFR3) signaling pathways are essential for normal longitudinal bone growth. Mutations in this receptor lead to various human growth disorders, including Achondroplasia, disproportionately short-limbed dwarfism, characterized by narrowing of the hypertrophic region of the epiphyseal growth plates. Here we find that FGF9, a preferred ligand for FGFR3 rapidly induces the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16253490
DOI: 10.1016/j.matbio.2005.07.003

Genes

FGF9
FGFR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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FGF upregulates osteopontin in epiphyseal growth plate chondrocytes: implications for endochondral ossification.PMID 16253490Read ↗

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