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Alphavirus Nucleocapsid Packaging and Assembly

20 Mar 2018

Abstract excerpt

Alphavirus nucleocapsids are assembled in the cytoplasm of infected cells from 240 copies of the capsid protein and the approximately 11 kb positive strand genomic RNA. However, the challenge of how the capsid specifically selects its RNA package and assembles around it has remained an elusive one to solve. In this review, we will summarize what is known about the alphavirus capsid protein, the packaging signal,...

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PMID: 29558394
DOI: 10.3390/v10030138

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