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Functional Analysis of the Murine Coronavirus Genomic RNA Packaging Signal

1 Mar 2013

Abstract excerpt

Coronaviruses selectively package genomic RNA into assembled virions, despite the great molar excess of subgenomic RNA species that is present in infected cells. The genomic packaging signal (PS) for the coronavirus mouse hepatitis virus (MHV) was originally identified as an element that conferred packaging capability to defective interfering RNAs. The MHV PS is an RNA structure that maps to the region of the...

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PMID: 23449786
DOI: 10.1128/jvi.00100-13

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