Article
Segmental duplications and gene conversion: Human luteinizing hormone/chorionic gonadotropin beta gene cluster.
Genome research - 1 Nov 2005
Hallast Pille, Nagirnaja Liina, Margus Tõnu, Laan Maris
Abstract excerpt
Segmental duplicons (>1 kb) of high sequence similarity (>90%) covering >5% of the human genome are characterized by complex sequence variation. Apart from a few well-characterized regions (MHC, beta-globin), the diversity and linkage disequilibrium (LD) patterns of duplicons and the role of gene conversion in shaping them have been poorly studied. To shed light on these issues, we have re-sequenced the human...
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