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Article

Recent duplication, domain accretion and the dynamic mutation of the human genome.

Trends in genetics : TIG - 1 Nov 2001

Eichler E E

Abstract excerpt

An estimated 5% of the human genome consists of interspersed duplications that have arisen over the past 35 million years of evolution. Two categories of such recently duplicated segments can be distinguished: segmental duplications between nonhomologous chromosomes (transchromosomal duplications) and duplications mainly restricted to a particular chromosome (chromosome-specific duplications). Many of these...

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PMID: 11672867
DOI: 10.1016/s0168-9525(01)02492-1

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