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Article

Human adaptation and evolution by segmental duplication.

Current opinion in genetics & development - 1 Dec 2016

Dennis Megan Y, Eichler Evan E

Abstract excerpt

Duplications are the primary force by which new gene functions arise and provide a substrate for large-scale structural variation. Analysis of thousands of genomes shows that humans and great apes have more genetic differences in content and structure over recent segmental duplications than any other euchromatic region. Novel human-specific duplicated genes, ARHGAP11B and SRGAP2C, have recently been described...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Segmental Duplications, Genomic

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Identifiers

PMID: 27584858
DOI: 10.1016/j.gde.2016.08.001
PMCID: PMC5161654

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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