Article
Parkinson's disease and LRRK2: frequency of a common mutation in U.S. movement disorder clinics.
Movement disorders : official journal of the Movement Disorder Society - 1 Apr 2006
Kay Denise M, Zabetian Cyrus P, Factor Stewart A, Nutt John G, Samii Ali, Griffith Alida, Bird Tom D, Kramer Patricia, Higgins Donald S, Payami Haydeh
Abstract excerpt
The G2019S mutation in the LRRK2 gene is reportedly a common cause of familial Parkinson's disease (PD) and may also have a significant role in nonfamilial PD. The objective of this study was to assess mutation carrier frequency in PD patients from movement disorder clinics in the United States, stratified by family history, age at onset, and geography; to determine carrier frequency in a large and...
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