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Article

Structural and functional abnormalities of retinal ribbon synapses due to Cacna2d4 mutation.

Investigative ophthalmology & visual science - 1 Aug 2006

Wycisk Katharina A, Budde Birgit, Feil Silke, Skosyrski Sergej, Buzzi Francesca, Neidhardt John, Glaus Esther, Nürnberg Peter, Ruether Klaus, Berger Wolfgang

Abstract excerpt

PURPOSE: In a spontaneous mutant substrain of C57BL/10 mice, severely affected retinal ribbon-type synapses have been described. The retinopathy was accompanied by a substantial loss in the activities of the second-order neurons. Rod photoreceptor responses were maintained with reduced amplitude, whereas cone activities were absent. This study was conducted to identify the genetic defect underlying this hitherto...

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Source

Identifiers

PMID: 16877424
DOI: 10.1167/iovs.06-0271

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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