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Risk of diabetic nephropathy in type 1 diabetes is associated with functional polymorphisms in RANTES receptor gene (CCR5): a sex-specific effect.

Diabetes - 1 Nov 2005

Mlynarski Wojciech M, Placha Grzegorz P, Wolkow Pawel P, Bochenski Jacek P, Warram James H, Krolewski Andrzej S

Abstract excerpt

Chemokines and their receptors have been implicated in the development of diabetic nephropathy. To determine whether the risk of diabetic nephropathy is influenced by two functional polymorphisms in the regulated upon activation normal T-cell expressed and secreted (RANTES) receptor gene (CCR5), we recruited patients with type 1 diabetes, including 496 case subjects with overt proteinuria or end-stage renal...

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Share to Chemokine CCL5
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diabetic Nephropathies

Share to Genetic Predisposition to Disease

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Share to Polymorphism, Genetic

Share to Receptors, CCR5

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Source

Identifiers

PMID: 16249462
DOI: 10.2337/diabetes.54.11.3331

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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