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Article

Chemokine receptor genotype is associated with diabetic nephropathy in Japanese with type 2 diabetes.

Diabetes - 1 Jan 2002

Nakajima Kunihiro, Tanaka Yasushi, Nomiyama Takashi, Ogihara Takeshi, Piao Lianshan, Sakai Ken, Onuma Tomio, Kawamori Ryuzo

Abstract excerpt

Glomerular infiltration of monocytes/macrophages occurs in diabetic patients with nephropathy, and chemokine receptor signals are thought to play a key role in the development of nephropathy. Recently, polymorphism of the chemokine receptor (CCR)2 coding region V64I and the CCR5 promoter region 59029 (G/A) have been identified. Accordingly, we evaluated the effects of these genotypes on diabetic nephropathy. CCR2...

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Source

Identifiers

PMID: 11756347
DOI: 10.2337/diabetes.51.1.238

Genes

CCR5
ACR
CCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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