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Article

MCP-1 and RANTES polymorphisms in Korean diabetic end-stage renal disease.

Journal of Korean medical science - 1 Aug 2007

Joo Kwon Wook, Hwang Young Hwan, Kim Jae Hyeon, Oh Kook Hwan, Kim Hyunho, Shin Hyoung Doo, Chung Woo Kyung, Yang Jaeseok, Park Kyong Soo, Ahn Curie

Abstract excerpt

Macrophage infiltration has been observed in the renal biopsy specimens of diabetic nephropathy (DN), and hyperglycemic state stimulates the renal expression of RANTES (regulated upon activation, normal T-cell expressed and secreted) and MCP- 1 (monocyte chemoattractant protein-1). Upregulation of RANTES and MCP-1 with infiltrating macrophages may play a crucial role in the development and progression of DN....

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Identifiers

PMID: 17728497
DOI: 10.3346/jkms.2007.22.4.611
PMCID: PMC2693807

Genes

CCR2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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