Article
[Current contribution of molecular biology in the diagnosis of hepatitis B].
Acta gastro-enterologica Belgica - 1 Jan 2000
Brenard R
Abstract excerpt
Recent advances in molecular biology had led to a better understanding of the pathology of hepatitis B virus. The polymerase chain reaction technique has shown that the genome of hepatitis B virus is highly variable. Mutations in the pre-core region are associated with HBe Ag negative chronic hepatitis and fulminant hepatitis B; moreover, rare cases of hepatitis due to HBV with mutations within the S gene have...
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