Breast Cancer Prognosis: A Genetic Code for Personalized Therapy

Abstract excerpt

<h4>Background: </h4> Breast cancer is distinguished in three different subtypes, based on clinical and molecular parameters: Luminal - HER2 - Basal type. Luminal carcinomas (which represent about 65% of the total) are distinguished by a particular heterogeneity of biological behaviour with disease recovery in about 40-50% and death in about two-thirds of these patients at 5 years from diagnosis, despite initial a...

Topics

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• Prognosis
• Biomarkers, Tumor
• Breast Neoplasms
• Gene Expression Profiling
• Gene Expression Regulation, Neoplastic
• Genetic Predisposition to Disease
• Molecular Targeted Therapy
• Practice Guidelines as Topic

Identifiers and source

Literature Corpus work

f8dec35a-1e68-52e6-b055-f996c740a2c8

DOI

10.21203/rs.3.rs-405661/v1