Article
RNA-interference knockdown of Drosophila pigment dispersing factor in neuronal subsets: the anatomical basis of a neuropeptide's circadian functions.
PloS one - 14 Dec 2009
Shafer Orie T, Taghert Paul H
Abstract excerpt
BACKGROUND: In animals, neuropeptide signaling is an important component of circadian timekeeping. The neuropeptide pigment dispersing factor (PDF) is required for several aspects of circadian activity rhythms in Drosophila. METHODOLOGY/PRINCIPAL FINDINGS: Here we investigate the anatomical basis for PDF's various circadian functions by targeted PDF RNA-interference in specific classes of Drosophila neuron. We...
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