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Article

nfi-I affects behavior and life-span in C. elegans but is not essential for DNA replication or survival.

BMC developmental biology - 20 Oct 2005

Lazakovitch Elena, Kalb John M, Matsumoto Reiko, Hirono Keiko, Kohara Yuji, Gronostajski Richard M

Abstract excerpt

BACKGROUND: The Nuclear Factor I (one) (NFI) family of transcription/replication factors plays essential roles in mammalian gene expression and development and in adenovirus DNA replication. Because of its role in viral DNA replication NFI has long been suspected to function in host DNA synthesis. Determining the requirement for NFI proteins in mammalian DNA replication is complicated by the presence of 4 NFI...

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Identifiers

PMID: 16242019
DOI: 10.1186/1471-213X-5-24
PMCID: PMC1277823

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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