Article
Polymorphisms at GSTM1 and GSTP1 gene loci and risk of prostate cancer in a South Indian population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2000
Vijayalakshmi K, Vettriselvi V, Krishnan M, Shroff Sunil, Vishwanathan K N, Jayanth Vikram R, Paul Solomon F D
Abstract excerpt
Inter-individual differences in cancer susceptibility may be mediated in part through polymorphic variability in the bioactivation and detoxification of carcinogens. The glutathione S-transferases (GSTs), which are active in detoxification of wide variety of carcinogens, have been consistently implicated as cancer susceptibility genes in this context. We here assessed the association of GSTM1 and GSTP1...
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