Article
Association of GSTM1 null allele with prostate cancer risk: evidence from 36 case-control studies.
PloS one - 1 Jan 2012
Wei Bingbing, Xu Zhuoqun, Zhou You, Ruan Jun, Cheng Huan, Xi Bo, Zhu Ming, Jin Ke, Zhou Deqi, Hu Qiang, Wang Qiang, Wang Zhirong, Yan Zhiqiang, Xuan Feng, Huang Xing, Zhang Jian, Zhou Hongyi
Abstract excerpt
BACKGROUND: Glutathione S-transferase M1 (GSTM1) is thought to be involved in detoxifying several carcinogens and may play a vital role in tumorigenesis. Numerous studies have evaluated the association between GSTM1 null/present polymorphism and risk of prostate cancer (PCa). However, the results remain inconsistent. To derive a more precise estimation, we performed a meta-analysis. METHODOLOGY/PRINCIPAL...
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