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Article

GSTP1 Ile105Val polymorphism and prostate cancer risk: evidence from a meta-analysis.

PloS one - 1 Jan 2013

Wei Bingbing, Zhou You, Xu Zhuoqun, Ruan Jun, Cheng Huan, Zhu Ming, Hu Qiang, Jin Ke, Yan Zhiqiang, Zhou Deqi, Xuan Feng, Zhou Hongyi, Wang Zhirong, Huang Xing, Wang Qiang

Abstract excerpt

BACKGROUND: Glutathione S-transferase P1 (GSTP1) is thought to be involved in the detoxification of reactive carcinogen metabolites. Numerous epidemiological studies have evaluated the association of GSTP1 Ile105Val polymorphism with the risk of prostate cancer. However, the results remain inconclusive. To derive a more precise estimation, a meta-analysis was performed. METHODOLOGY/PRINCIPAL FINDINGS: A...

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Identifiers

PMID: 23977100
DOI: 10.1371/journal.pone.0071640
PMCID: PMC3747220

Genes

GSTP1
GSTM1

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