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Article

Correlation of polyp number and family history of colon cancer with germline MYH mutations.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Oct 2005

Jo Won-Seok, Bandipalliam Prathap, Shannon Kristen M, Niendorf Kristin B, Chan-Smutko Gayun, Hur Chin, Syngal Sapna, Chung Daniel C

Abstract excerpt

BACKGROUND & AIMS: Affected individuals with biallelic MYH mutations are believed to display multiple adenomatous polyps without evidence of vertical transmission. Our goal was to determine the detection rate of germline MYH mutations in a high-risk gastrointestinal cancer clinic population by using polyp number as a selection criterion. METHODS: Patients were screened for the 2 most common MYH mutations: Y165C...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Cancer Treatments and Studies

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Share to Colorectal Neoplasms, Hereditary Nonpolyposis

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Source

Identifiers

PMID: 16234049
DOI: 10.1016/s1542-3565(05)00411-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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