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A Tumorigenic Subpopulation with Stem Cell Properties in Melanomas

15 Oct 2005

Abstract excerpt

Recent studies suggest that cancer can arise from a cancer stem cell (CSC), a tumor-initiating cell that has properties similar to those of stem cells. CSCs have been identified in several malignancies, including those of blood, brain, and breast. Here, we test whether stem cell-like populations exist in human melanomas. In approximately 20% of the metastatic melanomas cultured in growth medium suitable for human...

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PMID: 16230395
DOI: 10.1158/0008-5472.can-05-1343

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