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Therapeutic implications of cellular and molecular biology of cancer stem cells in melanoma

13 Jan 2017

Abstract excerpt

Melanoma is a form of cancer that initiates in melanocytes. Melanoma has multiple phenotypically distinct subpopulation of cells, some of them have embryonic like plasticity which are involved in self-renewal, tumor initiation, metastasis and progression and provide reservoir of therapeutically resistant cells. Cancer stem cells (CSCs) can be identified and characterized based on various unique cell surface and...

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PMID: 28137308
DOI: 10.1186/s12943-016-0578-3

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