Article
A-kinase-anchoring protein 95 functions as a potential carrier for the nuclear translocation of active caspase 3 through an enzyme-substrate-like association.
Molecular and cellular biology - 1 Nov 2005
Kamada Shinji, Kikkawa Ushio, Tsujimoto Yoshihide, Hunter Tony
Abstract excerpt
Caspase-mediated proteolysis is a critical and central element of the apoptotic process, and caspase 3, one of the effector caspases, is proposed to play essential roles in the nuclear morphological changes of apoptotic cells. Although many substrates for caspase 3 localize in the nucleus and cas...
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