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Article

Molecular evidence for the nuclear localization of FADD.

Cell death and differentiation - 1 Jul 2003

Gómez-Angelats M, Cidlowski J A

Abstract excerpt

The Fas-associated death domain (FADD) adaptor protein FADD/Mort-1 is recruited by several members of the tumor necrosis factor receptor (TNFR) superfamily during cell death activated via death receptors. Since most studies have focused on the interaction of FADD with plasma membrane proteins, FADD's subcellular location is thought to be confined to the cytoplasm. In this report, we show for the first time that...

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Share to Active Transport, Cell Nucleus
Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12815462
DOI: 10.1038/sj.cdd.4401237

Genes

FADD
NES

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Molecular evidence for the nuclear localization of FADD.PMID 12815462Read ↗

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