Article
Genome wide significant linkage in schizophrenia conditioning on occurrence of depressive episodes.
Journal of medical genetics - 1 Jul 2006
Hamshere M L, Williams N M, Norton N, Williams H, Cardno A G, Zammit S, Jones L A, Murphy K C, Sanders R D, McCarthy G, Gray M Y, Jones G, Holmans P, O'Donovan M C, Owen M J, Craddock N
Abstract excerpt
BACKGROUND: Schizophrenia shows substantial clinical heterogeneity. One common important clinical variable in presentation is the occurrence of episodes of major depression. METHODS: We undertook analyses in an attempt to detect loci that influence susceptibility to, or modify the clinical expression of, schizophrenia according to the occurrence of episodes of major depression. We used a logistic regression...
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