Article
Hyaluronan secretion by synoviocytes is mechanosensitive.
Matrix biology : journal of the International Society for Matrix Biology - 1 Dec 2005
Momberger T S, Levick J R, Mason R M
Abstract excerpt
Hyaluronan (HA) is an essential component of synovial interstitial matrix and synovial fluid, but the link between its production and joint use is unclear. HA secretion is enhanced by joint distension in vivo, but direct proof that synoviocytes exhibit mechanosensitive HA secretion is lacking. We tested this in vitro. Primary rabbit synoviocyte (PRS) cultures from microdissected synovial intima were subjected to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.