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Major Histocompatibility Complex Class I and II Allele Frequencies and Disease Associations in Mexicans: A Systematic Review and Meta-Analysis.

Archives of medical research - 1 Jul 2025

Pérez-Galicia Anahi, Lugo-Caballero Cesar, Martínez-Calvillo Santiago, Ortiz-Navarrete Vianey, Manning-Cela Rebeca G

Abstract excerpt

BACKGROUND: The major histocompatibility complex (MHC) plays a crucial role in immune responses and is associated with disease susceptibility. This study systematically reviews MHC class I and class II allele frequencies and their associations with diseases in the Mexican population from 1979 to 2023. METHODS: A systematic review following PRISMA guidelines was conducted. Reports were obtained from the Allele...

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PMID: 40199052
DOI: 10.1016/j.arcmed.2025.103201

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