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Article

Exploring SNP-SNP interactions and colon cancer risk using polymorphism interaction analysis.

International journal of cancer - 1 Apr 2006

Goodman Julie E, Mechanic Leah E, Luke Brian T, Ambs Stefan, Chanock Stephen, Harris Curtis C

Abstract excerpt

Several single nucleotide polymorphisms (SNPs) in genes derived from distinct pathways are associated with colon cancer risk; however, few studies have examined SNP-SNP interactions concurrently. We explored the association between colon cancer and 94 SNPs, using a novel approach, polymorphism interaction analysis (PIA). We developed PIA to examine all possible SNP combinations, based on the 94 SNPs studied in...

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Source

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Identifiers

PMID: 16217767
DOI: 10.1002/ijc.21523
PMCID: PMC1451415

Genes

GSTT1
CASP8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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