Article
A comparison of approaches for association studies of polymorphisms and colorectal cancer risk.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland - 1 Sept 2012
Ramsey S D, Holmes R S, McDermott C L, Blough D K, Petrin K L, Poole E M, Ulrich C M
Abstract excerpt
AIM: Meta-analyses have been used to evaluate associations between polymorphisms and colorectal cancer risk, but the quality of individual studies used to inform them may vary substantially. Our aim was to apply well-established quality-control criteria to individual association studies and then compare the results of meta-analyses that included or excluded studies that did not meet these criteria. METHOD: We...
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