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Article

Association of polymorphisms in ERCC2 gene with non-familial thyroid cancer risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 2005

Silva Susana N, Gil Octávia Monteiro, Oliveira Vanessa C, Cabral Marisa N, Azevedo Ana Paula, Faber Ana, Manita Isabel, Ferreira Teresa Cruz, Limbert Edward, Pina Julieta Esperança, Rueff José, Gaspar Jorge

Abstract excerpt

The ERCC2 protein is an evolutionary conserved ATP-dependent helicase that is associated with a TFIIH transcription factor complex and plays an important role in nucleotide excision repair. Mutations in this gene are responsible for xeroderma pigmentosum and also for Cocayne syndrome and trichothiodystrophy. Several single nucleotide polymorphisms have been identified in the ERCC2 locus. Among them, a G23591A...

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Identifiers

PMID: 16214924
DOI: 10.1158/1055-9965.EPI-05-0230

Genes

ERCC2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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