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Article

Atomic models by cryo-EM and site-directed spin labeling: application to the N-terminal region of Hsp16.5.

Structure (London, England : 1993) - 1 Aug 2005

Koteiche Hanane A, Chiu Steve, Majdoch Rebecca L, Stewart Phoebe L, Mchaourab Hassane S

Abstract excerpt

We report an approach for determining the structure of macromolecular assemblies by the combined application of cryo-electron microscopy (cryo-EM) and site-directed spin labeling electron paramagnetic resonance spectroscopy (EPR). This approach is illustrated for Hsp16.5, a small heat shock protein that prevents the aggregation of nonnative proteins. The structure of Hsp16.5 has been previously studied by both...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16084388
DOI: 10.1016/j.str.2005.05.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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