Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The EPAS1 gene influences the aerobic-anaerobic contribution in elite endurance athletes.

Human genetics - 1 Dec 2005

Henderson Jennifer, Withford-Cave Jason M, Duffy David L, Cole Stuart J, Sawyer Nicole A, Gulbin Jason P, Hahn Allan, Trent Ronald J, Yu Bing

Abstract excerpt

EPAS1 is a gene involved in complex oxygen sensing. It is expressed in microvascular endothelial cells, lung epithelial cells, cardiac myocytes and the brain. An association study was undertaken comparing elite endurance athletes classified into two groups according to a power-time model of performance intensity: power-time-maximum (PT-MAX; N=242, event duration 50 s to 10 min) and power-time-steady state (PT-SS;...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Basic Helix-Loop-Helix Transcription Factors
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Exercise

Share to Haplotypes

Share to Oxygen Consumption

Share to Polymorphism, Single Nucleotide

Share to Sports

Share to Transcription Factors

Source

Identifiers

PMID: 16208515
DOI: 10.1007/s00439-005-0066-0

Genes

EPAS1
MAX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The EPAS1 gene influences the aerobic-anaerobic contribution in elite endurance athletes.PMID 16208515Read ↗

EPAS1 is associated with human muscle fiber composition and endurance phenotypes.Semantic proximity Read ↗

EPAS1 gene variants are associated with sprint/power athletic performance in two cohorts of European athletes.Semantic proximity Read ↗

[Association between G/A - Polymorphism of EPAS1 gene and the maximal level of oxygen consumption in Russian athletes.Semantic proximity Read ↗

Down-Regulation of EPAS1 Transcription and Genetic Adaptation of Tibetans to High-Altitude Hypoxia.Semantic proximity Read ↗

Genetic variants in EPAS1 contribute to adaptation to high-altitude hypoxia in Sherpas.Semantic proximity Read ↗

Physiological and genomic evidence that selection on the transcription factor Epas1 has altered cardiovascular function in high-altitude deer mice.Semantic proximity Read ↗

[Energy power in mountains: difference in metabolism pattern results in different adaption traits in Tibetans].Semantic proximity Read ↗

Two functional loci in the promoter of EPAS1 gene involved in high-altitude adaptation of Tibetans.Semantic proximity Read ↗

Genotype scores in energy and iron-metabolising genes are higher in elite endurance athletes than in nonathlete controls.Semantic proximity Read ↗

Expression and Variations in EPAS1 Associated with Oxygen Metabolism in Sheep.Semantic proximity Read ↗

Quantitative trait loci for maximal exercise capacity phenotypes and their responses to training in the HERITAGE Family Study.Semantic proximity Read ↗

Genes and Athletic Performance: The 2023 Update.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.